Departament of chemical study of biologically active compounds of microbial origin

Founded in 1953. Head: Vladimir A. Korshun, DSc

Staff:

  • Korshun V.A., DSc, Laboratory Head
  • Sadykova V.S., DSc, Senior Researcher
  • Fedorova G.B., PhD, Senior Researcher
  • Tyurin A.P., PhD, Senior Researcher
  • Prokhorenko I.A., PhD, Senior Researcher
  • Georgieva M.L., PhD, Senior Researcher
  • Rogozhin E.A., PhD, Senior Researcher
  • Alferova V.A., Junior Researcher
  • Baranova A.A., Junior Researcher, PhD Student
  • Shuvalov M.V., PhD, Engineer
  • Kudryakova G.H, PhD, Engineer
  • Koshina E.V., Engineer
  • Kulyaeva V.V. Engineer <
  • Stepashkina E.A., Technician
  • Shurachtenkova A.I., Technician
  • Slyundina M.S., Research Assistant

Main Research Areas:

  • Screening of producing stains for new antibiotics
  • Selection and creation of a collection of strains of microorganisms - producers of biologically active metabolites
  • Investigation of principles of production of biologically active metabolites
  • Isolation, purification and identification of biologically active compounds
  • Structure elucidation
  • Development of novel approaches to screening, isolation and structure elucidation of new natural compounds

Major Achievements:

  • Over 110 antibiotics were isolates and identified
  • Structure of 48 new antibiotics were elucidated
  • Industrial production processes for 13 antibiotics were developed
  • Systematic methods of drug discovery were worked out

You can see the list of publications of laboratory staff HERE

Current Research Collaborations:

  • Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow
  • Lomonosov Moscow State University
  • Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University
  • Sukachev Institute of Forest SB RAS, Federal Research Center SB RAS
  • Engelhardt Institute of Molecular Biology of Russian Academy of Sciences
  • N.D. Zelinsky Institute of Organic Chemistry
  • Central Research Institute of Epidemiology, Laboratory of hospital infections
  • Moscow Scientific and Practical Tuberculosis Center
  • Institute of Cellular and Intracellular Symbiosis, Orenburg, Russian Federation.
  • Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, China
  • Biotechnology center of Ho Chi Minh city, Vietnam
  • Institute for Marine Sciences, Federal University of Ceara, Brazil
  • University of Delhi, India
  • University of Debrecen, Hungary
  • Institute of Physical Organic Chemistry National Academy of Sciences, Minsk, Belarus
  • Technische Universität Berlin, Germany
  • Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany
  • Laboratory of Genetics, Plant Sciences Group, Wageningen University, Netherlands

Research Projects:

  • RFBR Grant 15-04-06260 (2015–2017) Alkaliphilic and alkalitolerant filamentous fungi: distribution, molecular phylogeny and physiological features
  • RFBR–NNSF China Grant 17-53-53130 (2017–2018) Novel non-ribosomal peptide group antibiotics: structure and bioactivity

Contact Information:Тел.+7(499)246-6983; E-mail: gs-katrukha@mail.ru ; v-korshun@yandex.ru





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