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Публикации Лаборатории разработки методов поиска биологически активных соединений

  1. Тренин A.С., Лавренов С.Н., Мирчинк E.П., Исакова E.Б., Бычкова О.П., Копылова Т.М., Симонов А.Ю., Лакатош С.А., Цвигун Е.А. Разработка препаратов на основе трис(1-алкилиндол-3-ил)метана с целью преодоления лекарственной устойчивости возбудителей. //Антибиотики и химиотерапия 2016. Т.61. № 11-12.
  2. Тренин А.С. Методология поиска новых антибиотиков: состояние и перспективы. // Антибиотики и химиотерапия, 2015, Т.60, № 7-8. С 34-46.
  3. Тренин А.С., Бычкова О.П., Симонов А.Ю., Лакатош С.А. Новый класс химических соединений с антифунгальной активностью на основе производных 3-(N-аминоарил)малеимида. //Успехи медицинской микологии. 2015, Т. 14. С. 374.
  4. Тренин А.С., Бычкова О.П., Цвигун Е.А., Джавахян Б.Р., Тюрин А.П., Краснопольская Л.М. Образование ингибиторов биосинтеза стеролов культурой базидиального гриба Pleurotus eryngii. //Успехи медицинской микологии. 2015, Т. 14. С. 476-479.
  5. Тренин А.С. Методология поиска новых антибиотиков: состояние и перспективы. // Антибиотики и химиотерапия, 2015, Т.60, № 7-8. С 34-46.
  6. Тренин А.С., Кац Н.Ю., Цвигун Е.А., Бычкова О.П., Краснопольская Л.М. Базидиальные грибы Kuehneromyces mutabilis, Flammulina velutipes и Lentinus edodes, как возможные продуценты ингибиторов биосинтеза стеролов. // Успехи медицинской микологии, 2014, Т.12, с. 353-354.
  7. Тренин А.С., Бычкова О.П., Краснопольская Л.М. Микробные метаболиты – ингибиторы биосинтеза стеролов, образуемые грибами-базидиомицетами. // Научный фонд "БИОЛОГ" Ежемесячный научный журнал, 2014, №2, С.35-36. ISSN 2904-9520 http://biologyfond.ru/files/17-18.10.2014/bf2.pdf#page=35
  8. Trenin A.S., Kats N.Yu., Tsvigun E.A., Bychkova O.P., Krasnopolskaya L.M. Basidiomycetes Kuehneromyces mutabilis, Flammulina velutipes and Lentinus edodes as potential producers of inhibitors of sterol biosynthesis. // Progress in medicinal mycology. Materials of 6-th Allrussian congress in medicinal mycology, Moscow, 8-10 April 2014.. 2014, V.12, P. 353-354. ISBN 878-5-901578-16-2
  9. Trenin A.S., Lapchinskaya O.A., Pogozheva V.V., Gladkikh E.G., Bychkova O.P., Fedorova G.B., Katrukha G.S. Mutant strains of Amycolatopsis orientalis, Amycolatopsis fructiferi and Streptoallefeichus cremeus as producers of inhibitors of sterol biosynthesis. // Proceedings of the International Conference «Biotechnology and quality of life» (March 18-20, 2014, Moscow, Russia), Moscow: JSC “Expo-biochem-technologies”, D.I. Mendeleyev University of Chemistry and Technology of Russia, 2014 – 656 p. P. 148-149.
  10. Trenin A.S., Kats N.Yu., Tsvigun E.A., Bychkova O.P., Krasnopolskaya L.M.The possibility of development of new medicines on the base of Basidiomycetes // Proceedings of the International Conference «Biotechnology and quality of life» (March 18-20, 2014, Moscow, Russia), Moscow: JSC “Expo-biochem-technologies”, D.I. Mendeleyev University of Chemistry and Technology of Russia, 2014 – 656 p. P. 147.
  11. Trenin A.S., Kats N.Yu., Tsvigun E.A., Bychkova O.P., Krasnopolskaya L.M. Basidiomycetes, as a possible source of inhibitors of sterol biosynthesis. // Actual problems of nano-biotechnology and innovations with nontraditional natural resources and development of functional products. Materials of 6-th Russian theoretical and practical conference/ Ed. V.N.Zelenkov. Moscow. Rus Acad. Natur. Sci, 2013, 81 p., P.37-40.
  12. Trenin A.S., Tsvigun E.A., Bychkova O.P., Lavrenov S.N. Microbial model Halobacterium salinarum in screening of synthetic analogues of antibiotic turbomycin A with anticancer activity // Antibiotics and Chemotherapy, 2013, v.58, No 9-10, P.3-7.
  13. Trenin A.S. Microbial models in screening of inhibitors of sterol biosynthesis.// Antibiotics and Chemotherapy, 2013, v.58, No 7-8, P.3-14.
  14. Trenin A.S. Microbial model Halobacterium salinarum for screening of inhibitors of sterol biosynthesis. // Antibiotics and Chemotherapy, 2013, v.58, No 5-6, P.3-10.
  15. Trenin A.S. Microbial test-system for screening of inhibitors of sterol biosynthesis. // Antibiotics and Chemotherapy, 2013, v.58, No 3-4, P.3-9.
  16. Trenin A.S. Microbial metabolites inhibiting sterol biosynthesis: Their chemical diversity and characteristics of the mechanism of action. // Russian Journal of Bioorganic Chemistry, 2013, Vol. 39, No. 6, pp. 565–587.
  17. Tevyashova A.N., Olsufyeva E.N., Solovieva S.E., Printsevskaya S.S., Reznikova M.I., Trenin A.S., Galatenko O.A., Treshalin I.D., Pereverzeva E.R., Mirchink E.P., Isakova E.B., Zotchev S.B., Preobrazhenskaya M.N. Structure-Antifungal Activity Relationships of Polyene Antibiotics of the Amphotericin B Group // Antimicrobial Agents and Chemotherapy, 2013, V.57, N.8, P. 3815-3822.
  18. Кубанова А.А., Степанова Ж.В., Гуськова Т.А., Пушкина Т.В., Крылова Л.Ю., Шилова И.Б., Тренин А.С. Методические указания по изучению противогрибковой активности лекарственных средств. //В кн.: Руководство по проведению доклинических исследований лекарственных средств. Часть первая / Под ред. А.Н. Миронова. — М.: Гриф и К, 2012. — 944 с. С. 578-586.
  19. Lysenkova L.N., Turchin K.F, Korolev A.M., Bykov E.E., Danilenko V.N, Bekker O.B., Trenin A.S., Elizarov S.M., Dezhenkova L.G., Shtil A.A., Preobrazhenskaya M.N. A novel acyclic oligomycin A derivative formed via retro-aldol rearrangement of oligomycin A. // Journal of Antibiotics, 2012, 65 (8): 405-411.
  20. Lysenkova L.N., Turchin K.F., Korolev A.M., Danilenko V.N., Bekker O.B., Trenin A.S., Shtil A.A., Preobrazhenskaya M.N. Synthesis and properties of a novel brominated oligomycin A derivative. //J Antibiot (Tokyo). 2012, 65 (4): 223-225.
  21. Shashkov A. S., Tsvetkov D. E., Lapchinskaya O. A., Kulyaeva V. V., Fedorova G. B., Trenin A. S., Gladkikh E. G., Pogozheva V. V., Makarova M. O., Orlova G. I., Katrukha G. S., and Nifantiev N. E. Structure, 1H and 13C NMR spectra, and biological activity of the antibiotic INA-1278 related to irumamycin and produced by the experimental Streptomyces sp. strain No. 1278. //Russian Chemical Bulletin, International Edition, Vol. 60, No. 11, pp. 2412—2417, November, 2011.
  22. Stepanova E. V., Shtil’ A. A., Lavrenov S. N., Bukhman V. M., Inshakov A. N., Mirchink E. P., Trenin A. S., Galatenko O. A., Isakova E. B., Glazunova V. A., Dezhenkova L. G., Solomko E. Sh., Bykov E. E., Preobrazhenskaya M. N. Tris(1-alkylindol-3-yl)methylium salts as a novel class of antitumor agents. // Russian Chemical Bulletin. 2010 December, V. 59, N. 12, pp. 2259-2267.
  23. Preobrazhenskaya M.N., Olsufyeva E.N., Tevyashova A.N., Printsevskaya S.S., Solovieva S.E., Reznikova M.I., Trenin A.S., Galatenko O.A., Treshalin I.D., Pereverzeva E.R., Mirchink E.P., Zotchev S.B.. Synthesis and study of the antifungal activity of new mono- and di-substituted derivatives of a genetically engineered polyene antibiotic 28, 29-didehydro nystatin A1 (S44HP). //J.Antibiot., 2010, V.63, P.55-64.
  24. Trenin A.S., Zotchev S.B., Olsufyeva E.N., Tevyashova A.N., Solovieva S.E., Printsevskaya S.S., Galatenko O.A., Preobrazhenskaya M.N. Development of new antifungal drugs through chemical modification of macrolide antibiotics obtained as genetically engineered anti-fungal derivatives of antibiotic nystatin. //Int. Journal of Immunopathology, allergology and infectology (Part: Novel antifungals and industrial fungicides), 2009, No2, p.155-156.
  25. Trenin A.S., Soboleva N.U., Avtonomova A.V., Zvigun E.A., Fedorova G.B., Katrukha G.S., Isakova E.B., Bukhman V.M., Krasnopolskaya L.M. Estimation of antibiotic production by Lentinus edodes strains: Identification of antimicrobial, hypolipidemic and anticancer activity. ////Int. Journal of Immunopathology, allergology and infectology (Part: Future and applied fungal biotechnologies), 2009, No2, с.216-217.
  26. Trenin A.S., Zotchev S.B., Olsufyeva E.N., Tevyashova A.N., Solovieva S.E., Printsevskaya S.S., Galatenko O.A., Preobrazhenskaya M.N. New antifungal antibiotics generated through chemical modification of polyene macrolides: Elucidation of structure – activity correlation and selection of active derivatives. //Abstr. 5-th Moscow Int. Congress “Biotechnology: State of the art and prospects of development”. Moscow, Russia, 16-20 March 2009, part 1, p.87.
  27. Preobrazhenskaya M.N., Olsufyeva E.N., Solovieva S.E., Tevyashova A.N., Reznikova M.I., Luzikov Y.N.,. Treshalin I.D., Mirchink E.P., Bukhman V.M., Sletta H., Zotchev S.B. Chemical modification and biological evaluation of new semi-synthetic derivatives of 28, 29-didehydro nystatin A1 (S44HP), a genetically engineered anti-fungal polyene macrolide antibiotic. // Journal of Medicinal Chemistry, 2009, v.52, No1, pp.189-196.
  28. Terekhova L.P., Galatenko O.A., Trenin A.S., Tolstykh I.V., Zenkova V.A., Zhukhlistova N.E., Olkhovatova O.L, Malkina N.D., Boikova YU.V., Ustinova E.V., Katrukha G.S. Isolation and study of antibiotic INA-1132 (chlorothricin), produced by the strain Streptomyces baarnensis. // Antibiotics and Chemotherapy, 2008, v.53, No7-8, pp.3-7.
  29. Trenin A.S., Dudnik Yu.V. Solid phase template RNA-directed DNA-polymerase system in the screening of new antibiotics – potential HIV inhibitors. // Antibiotics and Chemotherapy, 2006, v.51, No10-11, pp.4-12.
  30. Trenin A.S. Solid phase template RNA-directed DNA-polymerase system in the screening of new antibiotics. //Abstr. 6-th Int. Forum “Biotechnology and present”. St-Petersburg, Russia, 1-2 June 2005, p.39-40.
  31. Trenin A.S., Terekhova L.P., Tolstykh I.V., Zenkova V.A., Fedorova G.B., Katrukha G.S. Screening of microbial secondary metabolites inhibiting cholesterol biosinthesis with the use of Hepatoblastoma G2 cell culture. //Antibiotics and Chemotherapy, 2003, v.48, No1, pp.3-8.
  32. Trenin A.S., Fedorova G.B., Laiko A.V., Dudnik Yu.V. UV-irradiation and regeneration of protoplasts of Amycolatopsis orientalis subsp. eremomycini for increasing of eremomycin production. //Antibiotics and Chemotherapy, 2003, v.46, No3, pp.6-11.
  33. Trenin A.S., Tolstykh I.V., Terekhova L.P., Zenkova V.A., Makarova M.O., Gladkikh E.G., Bychkova O.P., Katrukha G.S, Dudnik Yu.V. Hypolipidemic action of antibiotic 86/88 (Enniatin B) in Hepatoblastoma G2 cell culture. // Antibiotics and Chemotherapy, 2000, v.45, No4, pp.6-9.
  34. Leontyeva O.V., Trenin A.S., Bukhman V.M., Dudnik Yu.V. In vitro Cytotoxicity of mevalonate, lovastatin and carminomycin with respect to human malignant T lymphoblasts MOLT-4. //Antibiotics and Chemotherapy, 1999, V.44, No2, pp.13-18.
  35. Trenin A.S. Hypolipidemic action of ascofuranone in Hepatoblastoma G2 cell culture. // Antibiotics and Chemotherapy, 1999, v.44, No9, pp.7-9
  36. Trenin A.S. Fungal secondary metabolites that inhibit sterol biosynthesis (Review). //Applied Biochemistry and Microbiology, 1998, v.34, No. 2, pp.117-123.
  37. Trenin A.S., Olsuf'eva E.N. The mechanism of resistance to glycopeptide antibiotics as the basis for the development of novel derivatives capable of overcoming the resistance. //Russian Journal Bioorganic Chemistry, 1997, v.23, No11, pp.757-772.
  38. Terekhova L.P., Trenin A.S., Ozerskaya S.M., Rudenskaya Yu.A., Maksimova T.S., Katrukha G.S., Tolstykh I.V., Zenkova V.A., Fedorova G.B., Potapova N.P., Kosykh V.A. Biosynthesis of ascofuranone by the fungus Paecilomyces variotii Bainier. //Microbiology, 1997, v.66, No 5, pp.510-514.
  39. Trenin A.S., Katrukha G.S. Antibiotics inhibiting the biosynthesis of cholesterol (A review). //Farmaceutical Chemistry Journal (PCJOAU), 1997, v.31, No9, pp.452-463.
  40. Trenin A.S. Resistance to glycopeptide antibiotics. // Antibiotics and Chemotherapy, 1996, v.41, No 5, P.49-60.
  41. Trenin A.S. Rapid methods and automation in microbiology and immunology. // Antibiotics and Chemotherapy, 1994, v.39, No 9-10, pp.50-62.
  42. Trenin A.S. Modern microbiological method in monitoring growth and secondary metabolism of microbial strains. Abstr. of 7-th Intern. Congress on Rapid Methods and Automation in Microbiology and Immunology. London 12-15 Sept. 1993, p.43.
  43. Trenin A.S. Heterogeneity of Corinebacterium diphtheria. // Journal Microbiol., 1986, No.6, P.92-97.
  44. Trenin A.S., Dudnik Yu.V. Regeneration of protoplasts of Micromonospora olivoasterospora. // Antibiotics, 1984, v.29, No 8, pp. 572-575.
  45. Trenin A.S. Reparation of damages caused by antitumoral antibiotic carmonomycin. // Vestnik AMS USSR, 1981. No.5, P.71-75.
  46. Trenin A.S. Induction of single-strand DNA-brakes in tumor cells by carminomycin. // Antibiotics, 1978, v.23, No 5, P. 400-403.







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